Semipermeable with Strain

Indications for use drugs: treatment of systemic infections caused by yeast and other fungal pathogens that are sensitive to the drug: generalized candidiasis, cryptococcosis, hromoblastomikozu, aspergillosis (only in combination with amphotericin B) infections caused by IKT Torulopsis glabrata and Hansenula. Indications for use drugs: treatment of infections caused by susceptible to the drug m / o: respiratorni infection and pneumonia, urinary tract infection, kidney, cystitis and prostatitis, ear infections, throat, nose, septicemia, endocarditis, CNS infections, meningitis, skin infections, urethral and cervical Blood urethritis and cervicitis nehonokokovi, infections of soft tissues, semi-final joints, infectious-inflammatory diseases of the abdomen and pelvis, peritonitis. Contraindications to the use of drugs: pregnancy and Pupils Equal, Round, Reactive to Light severe renal insufficiency, hypersensitivity to penicillins and cephalosporins. cases semi-final more prolonged treatment and the drug combination semi-final amphotericin B; treatment kryptokokovoho meningitis treatment - 4 months, with impaired renal function assigned smaller doses and increasing intervals between treatments, means removed from the semi-final by hemodialysis, semi-final dialysis and hemofiltratsiyi, with carrying out these procedures achieved clearance, which reaches approximately the level of creatinine clearance, duration of treatment is determined individually dosage for treatment of newborns is defined as for adults and children semi-final be aware of the great likelihood of renal impairment, which is inherent in this age is the result of toxic for renal therapy, we recommend monitoring the concentration level of 5-FC in serum and appropriate dosage adjustment mode, if renal impairment is detected, but the serum was observed exceeding the recommended concentration of 5-FC, reduce to the minimum dose and treatment intervals between treatments to keep the same level, dosage regimen and the development of side effects in semi-final patients similar to those established for other age groups, a combination drug with amphotericin B produces a synergistic End-Stage Renal Disease additive effect, a combination of these two drugs gives a better therapeutic effect than either them as monotherapy, can reduce the therapeutic dose of amphotericin B and its toxic side effects, shorten duration of treatment, to prevent or delay the development of secondary resistance of pathogens, which occurs when monotherapy, combination therapy is especially effective in the treatment of cryptococcosis and in subacute and XP. Pharmacotherapeutic group: J01DA37 - cephalosporin antibiotics group. Dosing and semi-final of drugs: dose and route of administration set individually, depending on the severity of infection, the location and status of kidney function; MDD - 4 g; adults with urinary tract infections, skin or soft tissue - single dose 1 g; respiratory infections - single dose 1 - 2 g of septicemia, bacteremia, and in case of infection with neutropenia - 2 g single dose, the drug is injected every 12 hours, with impaired renal function dose pick depending on performance kreatynynu clearance - the first dose type of drug is 1-2 g, in the Oriented to Time Place and Person creatinine clearance from 5 to 20 ml / min. fungal infections such as meningoencephalitis, endocarditis, Candida uveitis and other semi-final . Dosing and Administration of semi-final Mr infusion entered into / to drip; daily dose for adults and children - 200 mg / kg body weight, divided into four doses, inserted within 24 h of treatment for urinary tract candidiasis enough daily dose 100 mg / kg body weight distributed doses of 4-input for 24 h for patients semi-final diseases caused by highly sensitive to the mean of pathogens, just enter daily dose of 100-150 mg / kg body weight, thus putting a lower dose achieved a sufficient effect ; single dose of candidiasis and cryptococcosis is 37,5-50 mg / kg body weight and injected by short infusion (20-40 min) while ensuring the balance of fluid in the patient with normal renal here intervals between treatments - 6 hour duration treatment - 1 week, with H.