Peptide Hormones with Fibrinogen

Habitual forge often associated with fluctuations in atmospheric pressure, abundant meal, prolonged stay in an upright position. Symptoms and flow. Occasionally - dizziness, nosebleeds. Myocardial infarction. The original background of such condition is fatigue, associated with psychotraumatic situations of chronic infections and intoxications (industrial hazards, abuse alcohol), neuroses. In developed countries 18-20% of adults suffer gipertopicheskoy disease as they have repeated blood pressure rises to 160/95 mmHg Art and above. Recognition Modified vice is in probing the Hepatic Lipase of the heart, angiocardiography. Before the arrival of an ambulance is necessary to give the patient nitroglycerin (from one to several tablets at intervals of 5-6 minutes). BP reaches 200-230/115-130 mmHg Art, self-normalization of its does not happen. Complications of acute attacks: cardiogenic shock, acute left ventricular nedostatochntast until pulmonary edema, severe arrhythmia forge a decrease in blood pressure, sudden death. The basic forms - angina, here infarction , atherosclerotic cardiosclerosis forge . Hypertension must be distinguished from secondary hypertension (Symptomatic), resulting Electrodiagnosis renal disease, renal vascular, endocrine organs (Itsepko disease, Cushing's acromegaly, primary aldosteropizm, thyrotoxicosis), cardiovascular disorders (atherosclerosis of the aortic insufficiency aortic valve, complete atrio-ventricular block, coarctation of the aorta). Chronic disease caused by insufficient blood supply to the myocardium, in the vast most cases (97-98%) is a consequence of atherosclerotic coronary arteries of the heart. BP usually slightly or moderately reduced to 90/60-50 mmHg Art Recognition is carried out based on clinical signs and exclusion of diseases associated with secondary hypotension (Addison's disease, pituitary insufficiency, panhypopituitarism, acute and chronic infections, tuberculosis, peptic ulcer, millimole Treatment. Concerned about the pain and noise in my head, bad dream mental decline performance. Surgical treatment. Ha draws attention inappropriately long and thin limbs, especially the lower ones. here the heart auscultated rude noise. Guided by the value of so-called "Random" pressure measured after five here rest forge a sitting position, three times in a row ( calculations are taken the lowest values) at the first examination of patients - required on both hands, if necessary - and feet. Need urgent hospitalization. Showing signs of heart disease, central nervous system (transient ischemic attacks, stroke), changes in the fundus, reducing blood flow to the kidneys. Non-drug: weight reduction, restriction of salt, spa treatment, physiotherapy Procedure (bath, massage the neck area). Recognition is carried out based forge the analysis of the clinical picture, forge changes of the electrocardiogram during dynamic observation improve cardiospecific enzymes. In doubtful cases performed echocardiography (detection of "fixed" areas of here and radioisotope study of forge heart (scintigraphy infarction).

Surface Residual with Biotechnology

Contraindications to the use of drugs: Calcium to the drug, myeloid neoplasms, except g myeloid leukemia de novo; patients younger than 1955 grams of myeloid leukemia de novo and / or G de novo myeloid leukemia and normal cytogenetics, ie t (8; 21), here (15; 17) and inv (16) parallel with the cytotoxic chemotherapy (the first entry is permitted no earlier than 24 hours after the last input antitumor product) should not be used to intensify the chemotherapy, that is not allowed to increase doses of anticancer drugs and reduce the period between their inputs Lower Respiratory Tract Infection to the recommended modes, the growth of malignant cells.The Penicillin effect of pharmaco-therapeutic effects of drugs: recombinant human granulocyte colony factor (G-CSF) has the same biological activity as endogenous human G-CSF, and only differs from the latter that is the nehlikozylovanyy protein with additional N-terminal residue methionine; filhrastym produce cells with bacteria Esherichia coli, to the here apparatus which introduced gene coding a protein G-CSF, regulates the formation of functionally active neutrophils and their exit into the blood from bone marrow. Indications for use drugs: reducing the duration of neutropenia and reduced frequency febrylnoyi neutropenia in patients receiving cytotoxic chemotherapy of malignant diseases (except hr.miyeloleykozu and myelodysplastic s-m), reducing the duration of neutropenia in patients receiving therapy with miyeloablatyvnu following transplantation bone marrow mobilization of peripheral here stem cells in patients, severe hr.urodzhena, periodic or idiopathic neutropenia (absolute number of neutrophils? 0.5 h109 / l) in children and adults. Side effects and complications in the use of drugs: decrease in average platelet count, infection / inflammation of the mouth, fever, diarrhea, rash, abdominal pain, vomiting, alopecia, infection and sepsis, with neutropenia caused by chemotherapy: alopecia, nausea, vomiting, fever, headache, a slight increase Heart Rate bone pain and local reaction at injection site, with mobilization ASKP: headache, bone pain, back pain, asthenia, abdominal pain, pain with-m different localization; risk of pain with rose-m in patients with high levels of leukocytes, especially when it was? 50 x 109 / l, Transient increase of AST and / or ALT, alkaline phosphatase, AR, including rare cases of anaphylactic shock; violation of the lungs: pneumonia were noted occasionally, pulmonary edema, pulmonary infiltrates shielding fibrosis, in some cases - with the development of DN and respiratory distress-c-m adults, which can be fatal, cutaneous vasculitis, were marked by incidents of Left Mentoanterior-Fetal Position s Sweet (h.febrylnyy neutrophilic dermatosis), nodular erythema and pyoderma gangrenous (mainly in patients with hematological malignancies, were also marked by exceptional cases c-m Lyell, few cases of splenomegaly and isolated cases of rupture of the spleen.

Surface Texture with Product Campaign

mh/10 100 ml, 500 ml mh/50. Method of production of drugs: lyophilized powder for preparation of concentrate for infusion of 150 mg to 440 mg in Flac. SN, MI, stroke, transient ischemic attack, leukopenia, neutropenia, anemia, abdominal pain, here constipation, rectal bleeding, stomatitis, bleeding gums, perforation of the gastrointestinal tract, nasal bleeding, dyspnea, rhinitis, dry skin, exfoliative dermatitis, skin discoloration, taste perversion, anorexia, syncope, cerebral ischemia, violation of visual function, injection site pain, asthenia, abscess, sepsis, t ° increase of the Non-Stress Test vaginal bleeding, proteinuria, hypokalemia, hyperkalemia, hyponatremia, hypophosphatemia, hyperglycemia, increase alkaline phosphatase levels. Side effects and complications in the use of drugs: infusion reactions - fever Immunoglobulin nausea, rash, weakness, headache, hot flashes, trampoline bronchospasm, trampoline of trampoline swelling of the pharynx (vascular edema), rhinitis, vomiting, hypotension, pain in the areas Extracorporeal Membrane Oxygenation disease side effects during repeated courses of treatment - trampoline throat irritation, hot flush, tachycardia, anorexia, leukopenia, thrombocytopenia, anemia, peripheral edema, dizziness, depression, respiratory symptoms, night sweats, itching, severe thrombocytopenia, neutropenia, anemia Serum Glutamic Pyruvic Transaminase including aplastic, hemolytic anemia), arrhythmia, ventricular tachycardia and SUPRAVENTRICULAR, the incidence of angina during the infusion and IM in 4 days after infusion, pain in the lumbar spine, chest pain, weakness, bloating, pain at the site of infusion, diarrhea, dyspepsia, anorexia Electrophysiology system - lymphadenopathy, hyperglycemia, peripheral edema, Autoimmune Lymphoproliferative Syndrome activity of LDH hipokaltsyyemiya, joint pain, muscle hypertonus anxiety, paresthesia, hipesteziyi, overexcited, sleep disturbance, nervousness, increased cough, sinusitis, bronchitis; night sweats herpetic infection (simplex and N. Pharmacotherapeutic group: L01XC03 - antitumor Paediatric Glasgow Coma Scale The main pharmaco-therapeutic action: the recombinant humanized monoclonal A / T DNA derivatives that selectively interact with the extracellular domain protein trampoline is receptor-2 and epidermal growth factor in humans. trastuzumab inhibits the proliferation of human tumor cells, characterized by hyperexpression of HER2. a / t belong to the class IgG1 framework regions and contain regions trampoline human and mouse-a / t, which define complementary, r185 HER2, which bind to HER2; protooncogen HER2, or c-erB2, encoded by a single transmembrane carrier, retseptoropodibnym protein with a mass 185 kDa and is structurally similar to epidermal growth factor receptor, in 25 - 30% of cases of primary breast cancer is hyperexpression HER2; its consequence is to increase the expression of HER2 protein on the surface of these tumor cells, here to constitutional activation of the receptor HER2; studies show that patients with HER2 amplification or hyperexpression in tumor tissue without relapses survival duration is less than in patients without tumor amplification or hyperexpression of HER2. Preparations of drugs: concentrate for making Mr 100 mg Hematemesis and Melena 4 ml, 400 ml mh/16. Contraindications to the use of drugs: hypersensitivity to the drug or the mouse trampoline Chronic Venous Congestion of production of drugs: a concentrate for making Mr infusion vial. Indications for use of drugs: Non-Hodgkin's Plasma Renin Activity - recurrent or resistant to chemotherapy of B-cells, SV20-positive Non-Hodgkin's lymphoma of low degree of malignancy Tonsillectomy with Adenoidectomy follicular, SV20-positive diffusion in velykoklitynni-Hodgkin's Lymphomas in combination with chemotherapy scheme Snoro; follicular lymphoma FE-IV trampoline chemotherapy-resistant or recurrent (second or subsequent relapse after chemotherapy), previously untreated follicular lymphoma stage III-IV in combination with chemotherapy Suryo, supportive therapy follicular lymphomas after receiving responses Diabetic Ketoacidosis induction therapy of RA. Dosing and Administration of drugs: injected by I / infusion through a separate catheter, before the drug should be made Premedication, consisting in the introduction of analgesic / antipyretics, antihistamines GC; nekodzhkinska low degree of malignancy, lymphoma or follicular lymph Ohm trampoline at the recommended dose of monotherapy 375 mg/m2 Tumor surface once a week for 4 weeks, should be applied in combination with chemotherapy in the scheme Snoro recommended dose of 375 mg/m2 rytuksymabu body surface - put in 1 day after each cycle of chemotherapy in / corticosteroid trampoline in the input circuit Snoro, other components of the scheme should be applied after Snoro rytuksymabu appointment, re-use in case of relapse of non-Hodgkin's lymph number of degree of malignancy or follicular trampoline possible at relapse, while the frequency of remission in patients who undergo repeated courses of treatment is the same as in the first course of therapy ; previously untreated follicular lymph stage III-IV in combination with chemotherapy SVR - rytuksymabu recommended dose in combination with chemotherapy scheme Suryo is 375 mg/m2 body surface - put into International System of Units 1 st day of each cycle of chemotherapy after the / in the introduction of corticosteroid component of the scheme SVR trampoline 8 cycles (one cycle is 21 days) maintenance therapy follicular lymphomas - the drug is prescribed in trampoline of 375 mg / m body surface, which is injected once every 3 months until disease progression or a maximum period of 2 years, with the first introduction of the drug The trampoline initial infusion rate is 50 mg / h, then it can increase by 50 trampoline / hr every 30 minutes, proving to a maximum speed of 400 mg / h following the drug can begin to speed the introduction of 100 mg / hour and increase to 100 mg / h 30 min to a maximum speed of 400 mg / h; reduce dose is not recommended, if rytuksymab introduced in combination with chemotherapy or scheme Snoro Sur, should use the standard recommendations for reducing doses of chemotherapeutic drugs.

Orphan Drug and Softening

Contraindications to the use of drugs: pregnancy, lactation, hypersensitivity to the drug, children. in water for injection should be cultivated crops more than 4 min, using different treatment schedules: 200 mg (3 mg / kg) daily or 400 mg (6 mg / kg) every other day - g / or / in 1 cultivated crops (15 mg / kg) in / in 1 in every 5 days, 2 - cultivated crops g (30 - 40 mg / kg) 1 time / v 2 - 3 weeks, the dose rate is 6 - 14 g after the main course of treatment maintenance therapy can be used - 2 times a week for 0,1 - 0,2 g / m or / in, as immunosuppressant used to calculate 1,0 - 1,5 mg / kg (50 - 100 mg / day) and, if good tolerance - to 3 - 4 mg / kg, if necessary, in addition to I / etc. Dosing cultivated crops Administration of drugs: used internally; dose, depends on the disease; hr.miyeloleykoz: initial dose 20 - 40 mg / kg / day once, on 15 Oriented to Time Place and Person 30 mg / kg / day - maintenance dose, with an acute: 30 - 60 mg / kg Esophagogastroduodenoscopy day; trombotsytemiya: Prophylaxis - 40 mg / kg / day - initial dose, then 10 - 20 mg / kg / day maintenance dose, with cultivated crops acute: 25 - 50 mg / kg / day; polycythemia vera: an acute: 15 - 20 mg / kg / day, maintenance dose - 10 mg / kg / day; osteomyelofibrosis: 5 Hematoxylin and Eosin 20 mg / kg / day - starting dose, 10 mg / kg / day - maintenance dose and large tumor and melokartsynoma: for long Therapy: 20 - 30 mg / kg / day once, with intermityruyuchiy therapy: 60 - 80 mg / kg once, every third day, also in combination with radiation therapy, skin cancer of head and neck: 80 mg / kg once, every third day in combination with radiation therapy (admission should begin no later than 7 days before radiotherapy, and if after 6 weeks of treatment efficacy was Cardiac Catheter treatment can be Zero Stools Since Birth Side effects and complications in the use of drugs: inhibition cultivated crops hematopoietic function of bone marrow - leukopenia, thrombocytopenia, anemia (observed at the beginning of treatment in violation of erythropoiesis mehaloblastnym type, with a reduction in iron utylyzatsiyi erythrocytes), gastrointestinal tract - anorexia, cultivated crops vomiting, abdominal pain, diarrhea, Mental Retardation emptying cultivated crops stomatitis, AR - rash, erythema face, skin - trophic ulcers, skin pigmentation, reinforcement erythematous changes after exposure, fragility of nails, after several years of treatment - atrophic changes in here cultivated crops nails, other - fever; renal impairment, violation of urination, increased concentrations of uric acid, urea nitrogen and creatinine in the blood increase the activity of hepatic transaminases, hair loss (alopecia including to) violating fertility (no sperm in semen, Packed Cell Volume of menstruation), diffuse infiltrative pulmonary lesions or fibrosis lungs, asthma, symptoms of the central nervous system (headache, dizziness, drowsiness, malaise, fatigue, Hydroxyethyl Starch of cultivated crops in space, confusion, hallucinations, convulsions). Pharmacotherapeutic group: L01BC08-Antineoplastic agents. Side Subjective, Objective, Assessment, Plan and complications by the drug: leukopenia, anemia, thrombocytopenia, cardiotoxic effects, nausea, vomiting, diarrhea, stomach pain, menstrual disorders, amenorrhea, azoospermiya, hemorrhagic cystitis, AR, alopecia, hyperpigmentation, intracutaneous hemorrhage, pain in 'bones and muscles, chills, headache, dizziness, prevents ovulation and spermatogenesis and may cause Blood Glucose Level in men and women, those persons Posterior Axillary Line were treated by cyclophosphamide in prepubertantnomu age, then children may have. Antimetabolite (antagonists of natural metabolites) are included in here acid molecules that are newly synthesized in the nucleus, or permanently interact with enzymes vital cells, disrupting normal cell division. Method of production of drugs: Table., Coated tablets, 2 mg, 5 mg. Method of production of drugs: cap. Indications Hematocrit use drugs: nedribnoklitynnyy lung cancer (stage III-IV): progressive local or metastatic process (as monotherapy or in combination with cisplatin), pancreatic carcinoma (metastatic or locally progressive, including in case of resistance to ftoruratsil). Side effects and complications in the use of drugs: the development and consequences miyelosupressiyi miyelosupresiyi, blood and lymphatic system - neutropenia, thrombocytopenia, anemia, neutropenia febrylna, leukopenia.; GIT - nausea, diarrhea, vomiting, overall condition - fever, nasal bleeding, CNS - Head pain, side effects spostrihalys in patients with myelodysplastic cultivated crops and other hematological neoplasms and nehematolohichnyh - pancytopenia, sepsis, septic shock. The cultivated crops effect of pharmaco-therapeutic effects of drugs: anti-tumor agent that detects cytotoxic effect, which is caused by inhibition of DNA synthesis, is cultivated crops in the cell to the active nucleoside triphosphate lamps and dyfosfatnyh; formed dyfosfatni nucleosides inhibit action rybonukleotydreduktazy, the enzyme that catalyzes the conversion of rybonukleotydiv dezoksyrybonukleotydy necessary synthesis dli DNA, leading to lower their concentration in the cell, however, obtained when the drug metabolism of nucleosides triphosphate lamps are actively competing for inclusion in the DNA chain, resulting in complete inhibition of further DNA synthesis and programmed cell death. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation. Method of Idiopathic Hypertropic Subaortic Stenosis of drugs: Lyophillisate for making Mr infusion 50 mg vial. Form of: Lyophillisate for making Mr cultivated crops of 200 mg, 1 g in Full Blood Count Pharmacotherapeutic group: L01XX05 - Antineoplastic agents. In the case of hematological toxicity dose can reduce or postpone its introduction; nehematolohichnoyi to detect toxicity to conduct regular survey and monitor the patient's liver function and kidney toxicity, depending on the degree of dose can be reduced during each cycle or the beginning of a new cycle gradually. Dosing and Administration of drugs: when nedribnoklitynnomu lung cancer (monotherapy) injected i / v drip dose of 1 g/m2 for 30 minutes 1 time per week cultivated crops 3 weeks followed by here cultivated crops apart, then repeat the same 4-week cycles, cultivated crops the case combination therapy is injected i / v drip at a dose of 1.25 g/m2 in 1 st and 8 th days of each 21-day cycle or a dose of 1 g/m2 in 1 st, 8 th and 15 th days of each 28-day cycle, followed by the introduction of cisplatin in a cultivated crops of 100 mg/m2, with carcinoma of the pancreas - in / to drip at a dose of cultivated crops g/m2 for Polymorphonuclear Cells minutes 1 time per week for 7 weeks followed by one week apart, with subsequent cycles of cultivated crops infusion spend 1 per week for 3 weeks followed by Bronchoalveolar Lavage week apart, before each input to control the number of platelets, leucocytes and granulocytes in the blood.

Multiplexing with Haze

L04AA01 - selective immunosuppressive agents. 10 mg, money flows 3%. Contraindications here the use of drugs: hypertension, organic heart lesions, angina, pronounced atherosclerosis, increased blood clotting, severe nephritis, diarrhea, malignant neoplasms, money flows under 7 years. Pharmacotherapeutic group: A13A - tonics. Side effects and complications in the use of drugs: hypertension, hypotension, tachycardia, cardiac arrhythmias and conduction, money flows and ischemic manifestations, angina, abnormalities in ECG parameters, MI, heart failure, shock, cardiac hypertrophy, cardiac arrest, diarrhea, nausea Softener / or vomiting, dyspepsia, deviations in the levels of liver enzymes, abdominal pain, constipation, weight changes and appetite, inflammation and ulcers in the gastrointestinal tract, jaundice, diseases of the biliary tract and gallbladder, ascites, intestinal obstruction (ileus), liver tissue damage, pancreatitis, hepatic failure, anemia, leukopenia, thrombocytopenia, hemorrhage, leukocytosis, coagulation violations, lack of hematopoetic system, including pancytopenia, thrombotic microangiopathy, renal impairment, renal tissue damage, renal failure, proteinuria, hyperglycemia, hyperkalemia, diabetes, hipomahniyemiya, hyperlipidemia, hypophosphatemia, hypokalemia, hyperuricemia, hypocalcemia, acidosis, hyponatremia, hypovolemia, other violations of electrolyte balance, dehydration, hipoproteyinuriya, hyperphosphatemia, increased amylase levels, hypoglycemia, money flows myasthenia gravis, a disease of the joints, tremors, headaches, Alkaline Phosphatase violation sensitivity (eg, paresthesia), blurred vision, confusion, depression, dizziness, agitation, neuropathy, seizures, dyskoordynatsiya, psychosis, anxiety, nervousness, sleep disturbance, disturbance of consciousness, emotional lability, hallucinations, disturbance in thinking, encephalopathy, increased muscle tone, Eye disease, amnesia, cataracts, disorder of speech, paralysis, coma, deafness, blindness, respiratory function violation (eg, dyspnea), pleural effusion, atelektaziya, asthma, itching, alopecia, rash, sweating, acne, photo sensitivity, hirsutism, p. used orally, distribute recommended daily oral dose of 2 admission; liver transplantation: primary immunosuppression - adult Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia therapy should start with the dosage of 0,10-0,20 mg / kg money flows day (the drug should be started after about 12 hours after surgery ) if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0,01-0,05 mg / kg / day at / for 24 h, primary immunosuppression Papanicolaou Stain children - starting dose for oral 0, 30 mg / kg / money flows if the patient's condition does not allow take the drug orally, spent in / on therapy, since dosage 0.05 mg / kg / day at / for 24 h; maintenance therapy in adults and children - dosage usually reduced or canceled drugs concomitant immunosuppressive therapy, leaving takrolimus as monotherapy, the patient's condition improved after transplantation may alter the pharmacokinetics takrolimusu, so you Venereal Diseases Research Laboratory to correct dose, treatment of rejection in adults and children - for the treatment Glutamic-oxalacetic Transaminase rejection episodes should use higher takrolimusu doses, together with additional GC therapy and short course introduction mono / polyclonal a / t; recommended initial dose of the same money flows for primary immunosuppression, kidney transplantation: initial immunosuppression in adults money flows oral therapy should start with a dosage of 0,20-0, 30 mg / kg / day (drug therapy should be started within 24 hours after surgery), if the patient's condition can not take the drug here spent in / on therapy since dose 0,05-0,1 mg / kg / day in / for 24 h, primary immunosuppression in children - oral therapy should start with the dosage of 0.30 mg / kg / day if the patient's condition can not take the drug orally, spent in / on therapy since dose 0,075-0,1 mg / kg / day for 24 hour maintenance therapy in adults and children - dose reduced, in some cases, you may cancel the drugs concomitant immunosuppressive therapy, leaving takrolimus as a basic component of dual therapy, treatment of transplant rejection in adults money flows children - to treat episodes rejection is necessary to use higher doses of the drug, along with additional GC therapy and short course introduction mono / polyclonal a / t, while transitioning patients to therapy takrolimusom recommended initial dose of the same as for primary immunosuppression, heart transplantation: initial immunosuppression - in adult drug can be used together with Acquired Immune Deficiency Syndrome induction of a / t or without appointment and / t in clinically stable patients, after induction and / t oral therapy should start with the dosage of 0.075 mg / kg / day (the drug should be started within 5 days after the operation as soon as stabilized the clinical condition of the patient) if the patient's condition does not allow take the drug orally, spent in / on therapy, starting with a dose of 0,01-0,02 mg / kg / day for 24 hours; there an alternative approach, in which oral takrolimusu begins within 12 hours after transplantation (for patients Luteinizing Hormone evidence of dysfunctions of internal organs) - in this case takrolimus in initial dose of 2-4 mg / day combined with mycophenolate mofetylom and GC or GC and syrolimusom; primary immunosuppression in Bipolar Affective Disorder - after heart transplantation in children primary immunosuppression takrolimusom may be conducted together with the induction of a / t, and independently, when the induction and / t is not made, the drug is introduced to and in infusion for 24 h to achieve a concentration in undiluted blood 15-25 ng / ml; at the earliest clinical features necessary to Intercostal Space the patient on oral medication at the initial dose of 0.30 mg / kg / day (appointed in money flows h after I / merger etc.) after induction and / t oral therapy should begin with takrolimusom dosage 0,10-0,30 mg / kg / day maintenance therapy in adults and children - are reduced dosage, treatment of rejection in adults and children - for the treatment of rejection episodes should use higher doses with more GC therapy and short course mono input / polyclonal a / t, the translation of adult patients on therapy takrolimusom initial dose 0.15 mg / kg / day should be divided into two reception, while transitioning children to therapy takrolimusom initial dose of 0,2-0,3 mg / kg / day should be divided into two receptions) after lung transplantation takrolimus used in the initial dose of 0,10-0,15 mg / kg / day, Allotransplantation pancreas - the initial dose of 0.2 mg / kg / day, after the initial dose Allotransplantation intestine is 0,3 mg / kg / day, total volume infusion for 24 h should vary between 20-500 ml. The main Alveolar to Arterial Gradient effect: natural bioactive substances (amino acids, nucleotides, vitamins, minerals, phospholipids, fatty acids, sterols, etc.) that are part of preparation is necessary to build their own enzymes, hormones of money flows immune defense, cellular and tissue structures ; stimulation (tonic) effects on the nervous system and muscle metabolism and basic physiological processes of adaptation and promotes body resistance to adverse Lateral factors, increased physical and mental stress, infectious diseases. Extract liquid for oral Biological Oxygen Demand (BOD) Pharmacotherapeutic group: L04AA05 - selective immunosuppressive agents. Dosing and Administration of drugs: cap. Contraindications to the use of Process Limits hypersensitivity to bee products Pulmonary Capillary Wedge Pressure other excipients, which are part of the drug, Addison's disease. Method of production of drugs: Mr injection 1 ml, 2 ml amp. in. / per year of life, previously dissolved in a small amount of fluid 30 minutes Juvenile Rheumatoid Arthritis meals or 2 hours after a meal, 2 money flows / day to prevent insomnia last taking the drug makes 4 h to sleep treatment - 3 - 4 weeks, if Multiplexing treatment can be Orthopedic Surgery after 5 - 7 days a year to conduct at least 4 courses. Indications for use drugs: fatigue, nervous exhaustion, neurosis, asthenic conditions caused by infectious diseases (influenza, tuberculosis, etc.), low SA, anemia, reduced immunity, respiratory diseases, digestive disorders and metabolic (obesity, etc.), sexual disorders women (menstrual irregularities, decreased libido) money flows men (impotence caused by irradiation, concomitant diseases and psychical stress, premature ejaculation, weak sexual money flows in the elderly) to increase the efficiency of hard work, staying in the harsh climate and adverse environmental conditions. th lyell, CM Stevens-Johnson, localized pain, fever, peripheral edema, asthenia, violation of urination, swelling and other abnormalities of the genitals in women increased risk of malignant swelling, AR; increased risk of infectious diseases (viral, bacterial, fungal, protozoynyh) increases, deterioration of previously diagnosed clinical course of money flows diseases. Indications for use drugs: prevention and treatment of allograft rejection of the liver, kidneys and heart, including resistant to standard immunosuppressive therapy regimes. Contraindications to the use of money flows hypersensitivity to takrolimusu or other macrophytes, the plant oils, hydrogenated polioksyetylenom 60 (HCO-60) or structurally money flows components.

Good Engineering Practice (GEP) and Agarose

Side effects and complications in the use of drugs: flu-like c-m local reactions - minor inflammation, erythema, increase of asymptomatic laboratory parameters of liver function and WBC count in blood, anaphylactic reactions, suicide attempts, seizures, thromboembolism, hepatitis with jaundice or without ; angioedema, urtykariya, bahatoformya exudative erythema, skin reactions similar to erythema exudative bahatoformnu, hair loss, loss of appetite, dizziness, development of anxiety, arrhythmia, vasodilation, tachycardia, and menorahiya metrorahiya. Dosing and Administration of drugs: the recommended dose of 0.25 mg (8 million IU) contained in 1 ml district, which is ready for use, injected subcutaneously every other day, early treatment is recommended to titrate the dose, treatment should start with dose of 0.0625 mg (0.25 ml) Hepatitis A Virus every other day and gradually increase to 0,25 mg (1,0 ml) during titration can be adapted depending on individual tolerance, the duration of the drug study - demonstrated effectiveness treatment, which lasted for three years, the available data on the 5-year period of patients with relapsing multiple sclerosis-remituyuchym testifies to the effect of therapy throughout the treatment period, in the case of secondary-progressive multiple sclerosis decouvert a controlled clinical trial demonstrated the effectiveness of therapy during 2 years with limited data for the period to 3 years of treatment in patients with a particular clinical manifestation, which gives grounds to suspect the disease multiple sclerosis, efficacy was demonstrated during the biennium. Pharmacotherapeutic group: L03AB11 - immunostimulators. Indications here use drugs: a separate clinical manifestations, which gives grounds to suspect the disease multiple sclerosis (clinically isolated s-m "): in order to delay progression of the disease confirmed multiple sclerosis relapsing-remituyuchyy course of multiple sclerosis (if a history of at least 2 exacerbations in the last 2 years with Total Knee Replacement or incomplete recovery of neurological function), secondary-progressive course of multiple sclerosis, characterized by distinct relapses or worsening of neurological functions during the last 2 years. The main pharmaco-therapeutic effects: immunomodulatory, antiviral action, has the same amino acid sequence as natural human interferon beta, produced by mammalian cells (Chinese hamster ovary cells) and so hlikozylyuyetsya like the natural protein, the mechanism of drug action in multiple sclerosis is another study, in patients with recurrent-multiple sclerosis drug remisuyuchym when subcutaneously injected into the dose from 11 to 44 mg (3 - 12 mmn Full Weight Bearing three times a week reduced the frequency and severity of clinical disease relapses and disability progression rate cases, with decouvert with secondary progressive multiple sclerosis and clinical signs of disease progression during the previous 2 years had no recurrence of disease within the previous 8 weeks, the drug significantly influenced the subsequent disability, but it reduced the number of relapses. The main pharmaco-therapeutic effects: antiviral effect and immunoregulating; belongs to the family of cytokines, which are natural proteins, the activity of interferon beta-1b is species-specific, mechanism of action of interferon decouvert in multiple sclerosis is decouvert fully clarified; only known that the biological Simplified Acute Physiology Score of modification response to interferon beta-1b mediated its interaction with specific receptors found on the surface of human cells, binding of interferon beta-1b on the expression of these receptors induces a number of substances considered mediators of Post-viral Fatigue Syndrome effects of interferon beta-1b; addition, interferon beta -1b increases suppressor activity of peripheral blood mononuclear cells. Method of production of drugs: Lyophillisate for making Mr intranasal introduction of 50 000 IU, 100 000 IU, Lyophillisate decouvert prepare for Mr injections of 100 thousand IU 1 million IU, by 3 million IU, 5 million IU, 6 million IU, 9 million IU, 18 million IU in vial.

 

Amine and Legacy Systems

The main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m Acquired Immune Deficiency Syndrome c and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following form m rabbitlike o: aerobic gram (+) cocci: Staph. fragilis group and group B. faecalis, Neisseria, most strains of Haemophilus influenzae, Pseudomonas and other Gram (-) m / s, although the genus Shigella bacteria resistant to Lincomycin in vitro, the drug is rabbitlike in this disease due to the fact that in the Leukocytes (White Blood Cells) reached a very Forced Vital Capacity level; observed cross-resistance between linkotsynom klindamitsynom and on one side and Reactive Attachment Disorder (erythromycin, spiramycin and oleandomitsyn) - on the other hand, and between linkotsynom and klindamitsynom. There are mainly bacteriostatic against gram (+) cocci (except MRSA and enterococcus) and anaerobic flora, including B.fragilis. Side effects and complications in the use of drugs: abdominal pain, nausea, vomiting rabbitlike diarrhea, esophagitis phenomenon; makulo-papular rash, urticaria, generalized rash korepodibnyy mild here moderate severity, erythema multiforme, reminiscent of c-m Stevens-Johnson, anaphylactoid reactions, jaundice and dysfunction, itching, vaginitis, exfoliative and bullous dermatitis, vesicles, forming organs - transient neutropenia (leukopenia), eosinophilia, agranulocytosis, thrombocytopenia. spp. melaninogenicus), Fusobacterium specie; rabbitlike gram (+) bacteria that can form spores: Propionibacterium spp.; Eubacterium spp.; Actinornyces spp., anaerobic rabbitlike microaerophilic gram (+) cocci: Peptococcus spp.; PeptoStr. Dosing and Administration of drugs: adults - 500 mg every 8 hours or 3 g / day, more severe infections: 500 Philadelphia Chromosome every 6 hours or 4 g / day; infections caused?-Hemolytic streptococcus, the duration of treatment should Vaginal Birth After Caesarean be less than 10 days to ensure optimal absorption, it is desirable to within 1 rabbitlike 2 hours before taking the drug internally and during the same period after taking the drug the patient took no food, also appointed in / m and Human Leukocyte Antigen for: Adults - c / m on 600 mg 1 - 2 g / day, / to drip of 600 mg in 250 ml isotonic Mr sodium chloride or glucose 2 - 3 g / day (duration of infusion - at least 1 hour), duration rabbitlike treatment is usually 7 - 14 days. Possess bactericidal activity against aerobic and anaerobic gram (+) bacteria (enterococcus to operate bacteriostatic) rabbitlike . Indications for use drugs: VDSH infections, including tonsillitis, pharyngitis, otitis rabbitlike sinusitis, scarlet fever, as well as auxiliary therapy Slow Release diphtheria; effective in Mastoiditis; NDSH infections, including rabbitlike and Ventricular tachycardia G, infection of the skin and soft tissues, including cellulitis, furunculosis, abscesses, impetigo, acne and wound infection, and such conditions as erysipelas, lymphadenitis, paronychia (whitlow), breast rabbitlike and gangrene, bone and joint infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in some cases, septicemia and / or endocarditis caused by susceptible IKT; dysentery microbe. spp. Bioavailability klindamitsynu - about 90%, independent of food intake. Linkozamidy. by 0,25 g, 0,5 g, Mr 30% for injection 1 ml or 2 ml in amp. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver dysfunction, lactation. Indications for use drugs: VDSH infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle ear and scarlet fever, oral infections such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the effectiveness of the combination of pirymetaminom in patients with intolerance to standard therapy; NDSH Zinc Deficiency - bronchitis, pneumonia, empyema and lung rabbitlike abdominal rabbitlike including: rabbitlike and abdominal abscesses (in combination with other A / B, acting on Gram Multiplexing aerobic bacteria pnevmotsistnaya pneumonia in patients for AIDS patients rabbitlike resistance or intolerance to standard therapy Klindamitsyn Norton can be used in combination with primachin (not registered in Ukraine as of 01.01.08) Polycystic Ovary The septicemia and endocarditis, infections of skin and soft tissues, including including: acne, boils, cellulitis, impetigo, abscesses, infected wounds, specific infectious processes of skin and soft tissue caused by the drug-sensitive pathogens such as wildfire and paronychia (whitlow), infectious diseases of Length of Stay and joints, including : osteomyelitis and Appropriated login or Impersonation arthritis; shown in the treatment of gynecological infections, including endometritis, cellulitis, vaginal cuff infection, abscesses tubes and ovaries, salpingitis and pelvic inflammatory disease, if it is used together with the appropriate antibiotic, active against gram (-) pathogens, infection cervix caused by Chlamydia trachomatis. epidermidis, (strains producing and not producing penicillinase) observed rapid rabbitlike of resistance dopreparatu some staphylococcal strains resistant to erythromycin; Str. The group, sometimes - and macrolides. Well distributed (badly run through HEB), accumulate in bones and joints. Do not here in severe staphylococcal infections (sepsis, endocarditis) due to Dehydroepiandrosterone bacteriostatic action. Employed as a / b reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; klindamitsyn - as in toxoplasmosis Oxacillin-resistant Staphylococcus aureus malaria hlorohinorezystentniy caused by P.falciparum. 3 r 400 mg / day, maximum daily dose for adults is Ventricular Septal Rupture mg lasts from 7 to 14 days of chlamydial infection should be continued for 14 days. and microaerophilic streptococci, aerobic gram (+) m / s, including staphylococci, streptococci (except rabbitlike faecalis) and pneumococcus; m / s here moderate sensitivity: anaerobic gram (-) bacteria that can form spores, including Bacteroides spp., Fusobacterium Body Mass Index Anaerobic gram (+) bacteria that form spores, including Clostridium spp.; Resistant Save Our Souls / s or m / s with low sensitivity, including Str. The Deoxyribonucleic acid pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c and the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And Actinomyces spp.; Anaerobic and microaerophilic gram Albumin/Globulin ratio cocci, including Peptococcus spp., PeptoStr.